Doctor of Philosophy

dissertationPupil dilation measures provide a useful index of test-taking processes. Prior research has established a simple positive relationship between pupil dilation magnitude and (i) threat levels, (ii) task difficulty levels, and (iii) working memory capacity. Surprisingly few studies have investigated the interaction of these three pupil response drivers. Do they add in a linear fashion, like separate weights on a single scale (as the "load" metaphor suggests), or is their relationship more complicated? To test of this question, I used a 2 X (2 X 3) mixed experimental design with random assignment to working memory resource depletion and nondepletion groups. These groups completed two versions of the same task, where response inhibition is required repeatedly in the depleting but is not required in the nondepleting version. Next, all subjects completed a test (90 factor-multiple judgment items) that employed two levels of difficulty (easy and difficult) and three levels of threat (safe, partially cued threat, and fully cued threat). Testtaking pupil data were collected at 60 Hz using a Tobii eye-tracker. Results indicated that levels of threat and task difficulty independently contribute to pupil response magnitude and they do not moderate one another. Apparently, the effects of difficulty and threat are not moderated by resource depletion; however, this study lacked power to detect anything less than a strong depletion effect. Results indicate that test-taking pupil responses are sensitive to testing conditions (e.g., threat and difficulty), but it remains unclear whether these responses are also sensitive to priming conditions (e.g., resource depletion)

Master of Science

thesisVery few studies have investigated the construct validity of measures of masculinity. This study analyzed multitrait multimethod matrices of male and female subscale scores from the Male Role Norms Inventory-Revised (MRNI-R), the Conformity to Masculine Norms Inventory (CMNI), and the Gender Role Conflict Scale (GRCS). Six subscales were of interest. Specifically, measures of dominance, homophobia, restrictive emotionality, nonrelational sexuality, aggression, and self reliance were given to 176 undergraduates from a large university in Utah. Subscale correlations were compared to indicate convergent and discriminant validity, as well as method effects, for each masculinity measure. Generally, the measures performed slightly better among males than females and the multidimensional structure of the CMNI was supported. Surprisingly, results indicated modest or poor validity among many of the subscales. These results were explained in terms of a construct confound on the GRCS, a very high method effect for the MRNI-R, and inconsistency between constructs and definitions among the measures. Finally, a preliminary content analysis of masculinity scales generated hypotheses about convergence between masculinity science and other social science disciplines. Limitations of this study and recommendations for future research were noted

A Test of the Particle Paradigm in N-Body Simulations

We present results of tests of the evolution of small ``fluid elements'' in cosmological N--body simulations, to examine the validity of their treatment as particles. We find that even very small elements typically collapse along one axis while expanding along another, often to twice or more their initial comoving diameter. This represents a possible problem for high--resolution uses of such simulations.Comment: Uses aasms4.sty; accepted for publication in ApJ Letters. Files available also at ftp://kusmos.phsx.ukans.edu/preprints/ates

A semi-analytical solution for transient streaming potentialsassociated with confined aquifer pumping tests

We consider the transient streaming potential response due to pumping from a confined aquifer through a fully penetrating line sink. Confined aquifer flow is assumed to occur without fluid leakage from the confining units. However, since confining units are typically clayey, and hence more electrically conductive than the aquifer, they are treated as non-insulating in our three-layer conceptual model. We develop a semi-analytical solution for the transient streaming potentials response of the aquifer and the confining units to pumping of the aquifer. The solution is fitted to field measurements of streaming potentials associated with an aquifer test performed at a site located near Montalto Uffugo, in the region of Calabria in Southern Italy. This yields an average hydraulic conductivity that compares well to the estimate obtained using only hydraulic head data. Specific storage is estimated with greater estimation uncertainty than hydraulic conductivity and is significantly smaller than that estimated from hydraulic head data. This indicates that specific storage may be a more difficult parameter to estimate from streaming potential data. The mismatch may also be due to the fact that only recovery streaming potential data were used here whereas head data for both production and recovery were used. The estimate from head data may also constitute an upper bound since head data were not corrected for pumping and observation wellbore storage. Estimated values of the electrical conductivities of the confining units compare well to those estimated using electrical resistivity tomography. Our work indicates that, where observation wells are unavailable to provide more direct estimates, streaming potential data collected at land surface may, in principle, be used to provide preliminary estimates of aquifer hydraulic conductivity and specific storage, where the latter is estimated with greater uncertainty than the former

Effect of Loading Condition on Traction Coefficient Between Shoes and Artificial Turf Surfaces

Background. The interaction between a shoe and a turf surface is highly complex and difficult to characterize. Over the three decades since artificial turf was introduced, researchers have attempted to understand the traction caused by the interaction. However, some of the methodologies used for traction measurements have not capitalized on advances in currently available technology for testing and most testing conditions have not simulated realistic physiological loads. Method of Approach. To assess the effect of test condition on traction results, the newly designed TurfBuster testing device was used to collect traction data on FieldTurf™ brand artificial turf under varying conditions. Four cleated athletic shoes were tested under eight different vertical loads ranging from 222-1780 N. The static, dynamic, and peak traction coefficient values were calculated and averaged over three trials for each shoe and condition. Results. In all but the lowest vertical load condition, the static traction coefficient was less than the dynamic traction coefficient. There was a distinct separation found between 666 N and 888 N loading conditions for all three variables measured. Below the load condition of 666 N only one significant difference was found in all comparisons across and within shoe styles. Above 888 N multiple differences were found across shoe styles, but differences were not found within a shoe style until a load of at least 1554 N. Conclusions. At loads below 666 N the cleats perform almost identically at all three variables measured, static, dynamic, and peak traction coefficients. At loads above 888 N, shoe traction was different among the cleat styles for all traction variables. However, at loads between 888 N and 1334 N there were no differences found within a shoe style. This implies that each shoe has no performance difference in loads representative of up to one bodyweight. Due to these results the measurement of traction characteristics between cleated shoes and FieldTurf should be conducted at a load of at least 888 N to determine differences across shoe styles and loads ranging from 888 N to at least 1554 N to determine individual shoe characteristics

Influence of Towing Force Magnitude on the Kinematics of Supramaximal Sprinting

The purpose of this study was to determine the influence of towing force magnitude on the kinematics of supramaximal sprinting. Ten high school and collegiate aged track and field athletes ran 60m maximal sprints under 5 different conditions: non-towed (NT), Tow A (2.0% body weight), Tow B (2.8%BW), Tow C (3.8%BW), and Tow D (4.7%BW). Three-dimensional kinematics of a 4-segment model of the right side of the body were collected starting at the 35m point of the trial. Significant differences were observed in stride length (SL) and horizontal velocity of the center of mass (VH) during Tow C and Tow D. For Tow D, a significant increase in the distance from the center of mass to the foot at touchdown (DH) was also observed. Contact time (CT) decreased significantly in all towing conditions, while stride rate (SR) increased slightly (\u3c 2.0%) under towed conditions. There were no significant changes in joint or segment angles at touchdown, with the exception of a significant decrease in the flexion/extension angle at the hip during the Tow D condition. We concluded that towing force magnitude does influence the kinematics of supramaximal running. Furthermore, we suggest that coaches and practitioners adjust towing force magnitude for each individual and avoid using towing forces in excess of 3.8%BW

A structural bioinformatics approach for identifying proteins predisposed to bind linear epitopes on pre-selected target proteins

We have developed a protocol for identifying proteins that are predisposed to bind linear epitopes on target proteins of interest. The protocol searches through the protein database for proteins (scaffolds) that are bound to peptides with sequences similar to accessible, linear epitopes on the target protein. The sequence match is considered more significant if residues calculated to be important in the scaffold–peptide interaction are present in the target epitope. The crystal structure of the scaffold–peptide complex is then used as a template for creating a model of the scaffold bound to the target epitope. This model can then be used in conjunction with sequence optimization algorithms or directed evolution methods to search for scaffold mutations that further increase affinity for the target protein. To test the applicability of this approach we targeted three disease-causing proteins: a tuberculosis virulence factor (TVF), the apical membrane antigen (AMA) from malaria, and hemagglutinin from influenza. In each case the best scoring scaffold was tested, and binders with Kds equal to 37 μM and 50 nM for TVF and AMA, respectively, were identified. A web server (http://rosettadesign.med.unc.edu/scaffold/) has been created for performing the scaffold search process with user-defined target sequences

Quantum-dynamical Modeling of the Rydberg to Valence Excited-State Internal Conversion in Cyclobutanone and Cyclopentanone

In this paper we present 4-state, 5-dimensional Vibronic Coupling Hamiltonians for cyclobutanone and cyclopentanone. Wave packet calculations using these Hamiltonians reveal that for cyclobutanone the (n,3s) to (n,π*) internal conversion involves direct motion in nuclear modes coupling the two states leading to fast population transfer. For cyclopentanone, internal vibrational energy redistribution is a bottleneck for activating reactive nuclear modes leading to slower population transfer